Guangdong Researchl Institute of Gastroenterology and Guangdong Provincial Key Laboratory of Colorectal plus Pelvic Floor Disease Research is located in the sixth affiliated hospital of Sun Yat-sen University (Guangdong Province Gastrointestinal and Anal Hospital), with is configured with the central laboratory, molecular diagnostic laboratory, database, tissue bank, animal research facility. A total area is about 6000 ㎡, and a total value of equipment more than 50 million yuan. The Institute implements the project principal investigator (PI) system.