左涛(研究员,博士生导师)

       左涛,国家高层次青年人才,中山大学胃肠病学研究所副所长,中山大学人体微生态与慢病教育部重点实验室常务副主任,中山大学“百人计划”中青年杰出人才。WHO药物对肠道微生态健康工作组专家(全球6位),入选全球前2%顶尖科学家,获得美国消化道疾病学会(AGA)颁发的“青年研究奖”(连续2次)、Elsevier中国高被引学者、International Microbiology Literacy Initiative (IMiLI) 世界微生物科普倡议组成员、BMC Medicine编辑。以通讯作者、第一作者发表高水平SCI文章40余篇,其中IF>10的文章26篇。香港中文大学研究计划fellowship、英国研究和科创基金(UK Research and Innovation, UKRI) 评审专家 ,欧洲克罗恩病与结肠炎委员会(ECCO)青年委员、国际微生物病毒协会(ISVM)会员、美国微生物学会(ASM)会员、中国人体健康科技促进会肠道微生态与菌群移植专业委员会常务委员、中国医药教育协会微生态与健康专业委员会委员、广东省精准医学应用学会微生态医学分会委员、广东省精准医学应用学会长青智库工作委员会委员。


以独立通讯或最后通讯作者发表IF>10的文章13篇:
Cell Host & Microbe (1) 、Lancet Gastroenterology & Hepatology (1)、Lancet Microbe (2)、Nature Reviews Gastroenterology & Hepatology (1)、Nature Reviews Microbiology (1)、Nature Reviews Bioengineering (1)、Gut(2)、Microbiome (1) 、Gut Microbes (1)、Genomics, Proteomics, & Bioinformatics (1)、Journal of Medical Virology (1)


以第一作者(含共同)作者发表IF>10的文章15篇:
Cell Host & Microbe (1) 、Gut (5)、Gastroenterology (4)、Nature Reviews Gastroenterology & Hepatology (1)、Microbiome (1)、Nature Communications (2)等


任期刊审稿人: Cell、Lancet、Nature Medicine、Cell Host & Microbe、Nature Metabolism、Nature Immunology、Lancet Gastroenterology & Hepatology、Lancet Infectious Disease、Lancet Microbe、Nature Reviews Gastroenterology & Hepatology、Cell Reports Medicine、Nature Communications、Gut、Gastroenterology


团队研究方向:
1.肠道微生态(细菌、噬菌体、真菌)与人体健康的关系
2.肠道微生态(细菌、噬菌体、真菌)在炎症性肠病(IBD)和粪菌移植(FMT)中的作用
3.应用宏基因组学、微生物组学、代谢组学、蛋白组学、转录组学等多组学手段和分子生物学、动物生理学揭示肠道微生物与宿主整体免疫和粘膜免疫的关系
4.通过转化医学(临床医学和基础医学)研究实现肠道微生态与消化道内、外疾病的致病机理和治疗的探索


Email: zuot@mail.sysu.edu.cn
Website: https://tender-galileo-cfcd4b.netlify.app
ORCID identifier: 0000-0001-8450-5281


PI教育和研究背景
2018.11-2020.12.21     香港中文大学,医学院               研究助理教授
2019.11-2020.12.21     香港肠道微生物研究MAGIC中心        科学家
2018.11-2020.12.21     香港中文大学,肠道微生物研究中心    研究助理教授
2015.11-2018.11       香港中文大学,医学院                   博士后
2014.8-2015.3         哈佛大学医学院、波士顿儿童医院      联合培养博士
2010.9-2015.6         中国海洋大学,食品科学                硕博连读
2006.9-2010.6         中国海洋大学,生物工程                  本科


代表性论文代表性项目荣誉

1.Runping Su, Weijie, et al, Tao Zuo*. Dietary whey protein protects against Crohn’s disease by orchestrating cross-kingdom interaction between the gut phageome and bacteriome. Gut, 2025. (最后通讯,影响因子: 23)
2.Cao, Z., Fan, D., Sun, Y. et al, Tao Zuo*. The gut ileal mucosal virome is disturbed in patients with Crohn’s disease and exacerbates intestinal inflammation in mice. Nature Communications 15, 1638 (2024). (最后通讯,影响因子:14.7)
3.Ziyu Huang, Yunyun Liu, Anna Phillips, Fen Zhang, Tao Zuo*. Varied prevalence and asymptomatic carriage of Cryptococcus gattii in the gut of Chinese populations. Lancet Microbe. 2025  (独立通讯,影响因子: 20.9)
4.Nengneng Li, et al, Tao Zuo*. Fecal phageome transplantation alleviates intermittent intestinal inflammation in IBD and the timing of transplantation matters: a preclinical, proof-of-concept study in mice. Gut, 2024. (独立通讯,影响因子: 23)
5.Tao Zuo*. Dark Matter Beyond the bacteria in fecal microbiota transplantation. Nature Reviews Gastroenterology & Hepatology, 2022. (独立通讯,影响因子:45.9)
6.Fen Zhang, Dominik Aschenbrenner, Ji Youn Yoo, Tao Zuo*. The gut mycobiome in health, disease, and clinical applications in association with the gut bacterial microbiome assembly. 2022. Lancet Microbe. (独立通讯,影响因子:20.9)
7.Nengneng Li, et al, Tao Zuo*. Fecal phageome transplantation alleviates intermittent intestinal inflammation in IBD and the timing of transplantation matters: a preclinical, proof-of-concept study in mice. Gut, 2024. (独立通讯,影响因子:23)
8.Bai, X., Sun, Y., Li, Y. et al, Tao Zuo*. Landscape of the gut archaeome in association with geography, ethnicity, urbanization, and diet in the Chinese population. Microbiome 10, 147 (2022). (最后通讯,影响因子: 13.8)
9. Bai, X., et al, Tao Zuo*. Engineering the gut microbiome. Nature Reviews Bioengineering. 2023 (最后通讯)
10.Tao Zuo*. Gut bacteriophages ignite the mammalian immunity. Nature Reviews Microbiology, 21, 634, 2023.  (独立通讯,影响因子: 69.2)
11.Ziyu Huang, Tao Zuo*. The gut microbiome: bridging medications and clinical outcomes post stem cell transplantation. Cell Host & Microbe (2023). (独立通讯,影响因子: 31.3)
12. Siu Lam, Xiaowu Bai, Andrey N Shkoporov, Heekuk Park, Xiaojian Wu, Ping Lan, Tao Zuo*. Roles of the gut virome and mycobiome in faecal microbiota transplantation. The Lancet Gastroenterology & Hepatology. (2022). (独立通讯,影响因子: 30.9)
13.Ziyu Huang, Yue Li, Heekuk Park, Martin Ho, Kanchan Bhardwaj, Naoki Sugimura, Hye Won Lee, Huicui Meng, Matthias P. Ebert, Kang Chao, Elke Burgermeister, Aadra P. Bhatt, Sudarshan A. Shetty, Kai Li1, Weiping Wen, Tao Zuo*. Unveiling and harnessing the human gut microbiome in the rising burden of non-communicable diseases during urbanization. Gut Microbes. 2023 (最后通讯,影响因子: 12.2)
14.Tao Zuo#, Qin Liu#, Fen Zhang# et al. Depicting SARS-CoV-2 fecal viral activity in association with gut microbiota composition in patients with COVID-19. Gut (2020). (第一作者,影响因子: 23)
15.Tao Zuo#, Yang Sun#, Yating Wan et al. Human Gut DNA Virome Variations across Geography, Ethnicity, and Urbanisation. Cell Host & Microbe (2020). (第一作者,影响因子:20.6)
16.Tao Zuo#, Fen Zhang# et al. Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization. Gastroenterology (2020). https://doi.org/10.1053/j.gastro.2020.05.048. (第一作者,影响因子:25.7)
17.Tao Zuo#, Hui Zhan# et al. Alterations in Fecal Fungal Microbiome of Patients With COVID-19 During Time of Hospitalisation until Discharge. Gastroenterology(2020). (第一作者,影响因子:25.7)
18.Tao Zuo, et al. Gut mucosal virome alterations in ulcerative colitis. Gut (2019): gutjnl-2018. (第一作者,影响因子:23)
19.Tao Zuo, Siew C Ng. Authors response: giant oversights in the human gut virome. Gut, gutjnl-2019. (2019)  (第一作者,影响因子:23)
20.Tao Zuo, Michael A. Kamm, Jean-Frédéric Colombel, Siew C Ng. Urbanization and the gut microbiota in health and inflammatory bowel disease. Nature Reviews Gastroenterology & Hepatology, 2018, 1. doi:10.1038/s41575-018-0003-z. (第一作者,影响因子:45.9)
21.Tao Zuo, Wong S H, Lam K, et al. Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome. Gut, 2018, 67(4):634-643. (第一作者,影响因子:23)
22.Tao Zuo, Sunny H Wong, et al. Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection. Nature Communications, 2018, doi: 10.1038/s41467-018-06103-6. (第一作者,影响因子:14.7)
23.Fen Zhang#, Tao Zuo#, Yun Kit Yeoh#, et al. Longitudinal dynamics of gut bacteriome, mycobiome and virome after fecal microbiota transplantation in graft-versus-host disease. 2020. Nature Communications (并列第一第二位, 影响因子:14.7).
24.Yang Sun#, Tao Zuo#, et al. Population-level configurations of gut mycobiome across six ethnicities in urban and rural China. 2021. Gastroenterolgoy (并列第一第二位,影响因子: 25.7)
25.Yun Kit Yeoh#, Tao Zuo#, et al. Gut microbiota composition reflects disease severity and dysfunctional immune responses in COVID-19 patients. Gut (2020). (并列第一第二位, 影响因子: 23)
26.Tao Zuo#, Liu Q#, Zhang F#, et al. Temporal Landscape of Human Gut virome in SARS-CoV-2 infection and severity. Microbiome. (2021) 9, 91. (第一作者,影响因子: 13.8)
27. Tao Zuo, Yun Kit Yeoh, Siew C Ng. Reply: The New Foe and Old Friends: Are We Ready for Microbiota-based Therapeutics in Treating COVID-19 Patients? Gastroenterolgoy (2021). (第一作者,影响因子: 25.7)
28.Zhirui Cao, Naoki Sugimura, Elke Burgermeister, Matthias P. Ebert, Tao Zuo*, and Ping Lan*. The gut virome: A new microbiome component in health and disease. eBioMedicine, 2022;81:104-113. (共同通讯,影响因子:9.7)
29.Tao Zuo*, Guangzhan Liang, et al. Baseline gut microbiome features prior to SARS-CoV-2 infection are associated with host symptoms in and post COVID-19. Journal of Medical Virology. 2023. (第一作者+共同通讯,影响因子:6.8)
30.Zuo T, Wu X, Wen W, et al. Gut Microbiome Alterations in COVID-19[J]. Genomics, Proteomics & Bioinformatics, 2021. (第一作者,影响因子:11.5)